PRIMARY LAB RESEARCH PUBLICATIONS
2022
Maternal-fetal transmission of delta-9-tetrahydrocannabinol (THC) and its metabolites following inhalation and injection exposure during pregnancy in rats
Baglot SL, VanRyzin JW, Marquardt AE, Aukema RJ, Petrie GN, Hume C, Reinl EL, Bieber JB, McLaughlin RJ, McCarthy MM, Hill MN. (2022)
Journal of Neuroscience Research 100(3):713-730
LINK
Sex and stressor modality influence acute stress-induced dynamic changes in corticolimbic endocannabinoid levels in adult Sprague Dawley rats
Vecchiarelli HA#, Morena M#, Lee TTY#, Nastase AS, Aukema RJ, Leitl KD, Gray JM, Petrie GN, Tellez-Monnery KJ, Hill MN (2022).
Neurobiology of Stress 20:100470
LINK
2021
Pharmacokinetics and Central Accumulation of Delta-9-Tetrahydrocannabinol (THC) and its Bioactive Metabolites Are Influenced by Route of Administration and Sex in Rats
Baglot SL, Hume C, Petrie GN, Aukema RJ, Lightfoot SHM, Grace LM, Zhou R, Parker L, Rho JM, Borgland SL, McLaughlin RJ, Brechenmacher L, Hill MN. (2021)
Scientific Reports 11(1):23990
LINK
Genetic Variants of Fatty Acid Amide Hydrolase Modulate Acute Inflammatory Responses to Colitis in Adult Male Mice
Vecchiarelli HA, Aukema RJ, Hume C, Chiang V, Morena M, Keenan CM, Nastase AS, Lee FS, Pittman QJ, Sharkey KA, Hill MN. (2021)
Frontiers in Cellular Neuroscience, 15:764706
LINK
Comorbid anxiety-like behavior in a rat model of colitis is mediated by an upregulation of corticolimbic fatty acid amide hydrolase.
Vecchiarelli HA, Morena M, Keenan CM, Chiang V, Tan K, Qiao M, Leitl K, Santori A, Pittman QJ, Sharkey KA, Hill MN. (2021)
Neuropsychopharmacology 46(5), 992-1003
LINK
Sex dependent effects of endocannabinoid modulation of fear extinction in rats.
Morena M, Nastase AS, Santori A, Cravatt BF, Shansky RM, Hill MN. (2021)
British Journal of Pharmacology 178(4), 983-996
LINK
2020
Stress-induced Modulation of Endocannabinoid Signaling Leads to Delayed Strengthening of Synaptic Connectivity in the Amygdala.
Yasmin F, Colangeli R, Morena M, Filipski S, Pittman QJ, van der Stelt M, Hillard CJ, Teskey GC, McEwen BS, Hill MN*, Chattarji S*. (2020)
Proceeding of the National Academy of Sciences USA 117(1), 650-655.
* = co-senior authorship
LINK
2019
Endocannabinoid Regulation of Homeostatic and Stress-induced Alterations in Food Intake in Male Rats.
Sticht MA, Lau DD, Keenan CM, Cavin JB, Morena M, Vemuri VK, Makriyannis A, Cravatt BF, Sharkey KA, Hill MN (2019)
British Journal of Pharmacology 176(10), 1524-1540.
LINK
Up-regulation of Anandamide Hydrolysis in the Basolateral Complex of the Amygdala Reduces Fear Memory Expression and Indices of Stress and Anxiety.
Morena M, Aukema R, Leitl K, Rashid A, Vecchiarelli HA, Josselyn SA, Hill MN (2019).
Journal of Neuroscience 39(7), 1275-1292.
LINK
2018
A Role for Fatty Acid Amide Hydrolase (FAAH) in the Leptin-mediated Effects on Feeding and Metabolism
Balsevich G, Sticht MA, Bowles NP, Singh A, Lee TT, Li Z, Chelikani P, Lee FS, Borgland SL, Hillard CJ, McEwen BS, Hill MN (2018)
Proceedings of the National Academy of Sciences USA 115(29), 7605-7610.
LINK
2016
Emotional Arousal State Influences the Ability of Amygdalar Endocannabinoid Signalling to Modulate Anxiety.
Morena M, Leitl K, Vecchiarelli HA, Gray JM, Campolongo P, Hill MN (2016)
Neuropharmacology 111, 59-69.
LINK
Acute Psychological Stress Modulates the Expression of Enzymes Involved in the Kynurenine Pathway throughout Corticolimbic Circuits.
Vecchiarelli HA, Gandhi CP, Hill MN (2016)
Neural Plasticity 2016, 7215684
LINK
Sustained Glucocorticoid Exposure Recruits Cortico-limbic CRH Signaling to Modulate Endocannabinoid Function.
Gray JM, Wilson CD, Lee TT, Pittman QJ, Deussing J, Hillard CJ, McEwen BS, Schulkin J, Karatsoreos IN, Patel S, Hill MN (2016)
Psychoneuroendocrinology 66, 151-158.
LINK
Divergent Responses of Inflammatory Mediators in the Amygdala and Prefrontal Cortex to Acute Psychological Stress.
Vecchiarelli HA, Gandhi CP, Gray JM, Morena M, Hassan KI, Hill MN (2016)
Brain, Behavior and Immunity 51, 70-91
LINK
2015
Corticotropin Releasing Hormone Drives Anandamide Hydrolysis in the Amygdala to Promote Anxiety.
Gray JM, Vecchiarelli HA, Morena M, Lee TT, Hermanson D, Kim AB, McLaughlin RJ, Hassan K, Kuhne C, Wotjak CT, Deussing JM, Patel S, Hill MN (2015).
Journal of Neuroscience 35(9), 3879-3892
LINK
A Peripheral Endocannabinoid Mechanism Contributes to Glucocorticoid-mediated Metabolic Syndrome.
Bowles NP, Karatsoreos IN, Li X, Vemuri VK, Wood JA, Li Z, Tamashiro K, Schwartz GJ, Makriyannis AM, Kunos G, Hillard CJ, McEwen BS, Hill MN (2015).
Proceedings of the National Academy of Sciences USA 112, 285-290
LINK
2013
Age of Stress Exposure Modulates Both the Immediate and Sustained Effects of Repeated Stress on Corticolimbic Cannabinoid CB1 Receptor Binding in Male Rats.
Lee TT, Hill MN (2013)
Neuroscience 249, 106-114.
LINK
Maternal-fetal transmission of delta-9-tetrahydrocannabinol (THC) and its metabolites following inhalation and injection exposure during pregnancy in rats
Baglot SL, VanRyzin JW, Marquardt AE, Aukema RJ, Petrie GN, Hume C, Reinl EL, Bieber JB, McLaughlin RJ, McCarthy MM, Hill MN. (2022)
Journal of Neuroscience Research 100(3):713-730
LINK
Sex and stressor modality influence acute stress-induced dynamic changes in corticolimbic endocannabinoid levels in adult Sprague Dawley rats
Vecchiarelli HA#, Morena M#, Lee TTY#, Nastase AS, Aukema RJ, Leitl KD, Gray JM, Petrie GN, Tellez-Monnery KJ, Hill MN (2022).
Neurobiology of Stress 20:100470
LINK
2021
Pharmacokinetics and Central Accumulation of Delta-9-Tetrahydrocannabinol (THC) and its Bioactive Metabolites Are Influenced by Route of Administration and Sex in Rats
Baglot SL, Hume C, Petrie GN, Aukema RJ, Lightfoot SHM, Grace LM, Zhou R, Parker L, Rho JM, Borgland SL, McLaughlin RJ, Brechenmacher L, Hill MN. (2021)
Scientific Reports 11(1):23990
LINK
Genetic Variants of Fatty Acid Amide Hydrolase Modulate Acute Inflammatory Responses to Colitis in Adult Male Mice
Vecchiarelli HA, Aukema RJ, Hume C, Chiang V, Morena M, Keenan CM, Nastase AS, Lee FS, Pittman QJ, Sharkey KA, Hill MN. (2021)
Frontiers in Cellular Neuroscience, 15:764706
LINK
Comorbid anxiety-like behavior in a rat model of colitis is mediated by an upregulation of corticolimbic fatty acid amide hydrolase.
Vecchiarelli HA, Morena M, Keenan CM, Chiang V, Tan K, Qiao M, Leitl K, Santori A, Pittman QJ, Sharkey KA, Hill MN. (2021)
Neuropsychopharmacology 46(5), 992-1003
LINK
Sex dependent effects of endocannabinoid modulation of fear extinction in rats.
Morena M, Nastase AS, Santori A, Cravatt BF, Shansky RM, Hill MN. (2021)
British Journal of Pharmacology 178(4), 983-996
LINK
2020
Stress-induced Modulation of Endocannabinoid Signaling Leads to Delayed Strengthening of Synaptic Connectivity in the Amygdala.
Yasmin F, Colangeli R, Morena M, Filipski S, Pittman QJ, van der Stelt M, Hillard CJ, Teskey GC, McEwen BS, Hill MN*, Chattarji S*. (2020)
Proceeding of the National Academy of Sciences USA 117(1), 650-655.
* = co-senior authorship
LINK
2019
Endocannabinoid Regulation of Homeostatic and Stress-induced Alterations in Food Intake in Male Rats.
Sticht MA, Lau DD, Keenan CM, Cavin JB, Morena M, Vemuri VK, Makriyannis A, Cravatt BF, Sharkey KA, Hill MN (2019)
British Journal of Pharmacology 176(10), 1524-1540.
LINK
Up-regulation of Anandamide Hydrolysis in the Basolateral Complex of the Amygdala Reduces Fear Memory Expression and Indices of Stress and Anxiety.
Morena M, Aukema R, Leitl K, Rashid A, Vecchiarelli HA, Josselyn SA, Hill MN (2019).
Journal of Neuroscience 39(7), 1275-1292.
LINK
2018
A Role for Fatty Acid Amide Hydrolase (FAAH) in the Leptin-mediated Effects on Feeding and Metabolism
Balsevich G, Sticht MA, Bowles NP, Singh A, Lee TT, Li Z, Chelikani P, Lee FS, Borgland SL, Hillard CJ, McEwen BS, Hill MN (2018)
Proceedings of the National Academy of Sciences USA 115(29), 7605-7610.
LINK
2016
Emotional Arousal State Influences the Ability of Amygdalar Endocannabinoid Signalling to Modulate Anxiety.
Morena M, Leitl K, Vecchiarelli HA, Gray JM, Campolongo P, Hill MN (2016)
Neuropharmacology 111, 59-69.
LINK
Acute Psychological Stress Modulates the Expression of Enzymes Involved in the Kynurenine Pathway throughout Corticolimbic Circuits.
Vecchiarelli HA, Gandhi CP, Hill MN (2016)
Neural Plasticity 2016, 7215684
LINK
Sustained Glucocorticoid Exposure Recruits Cortico-limbic CRH Signaling to Modulate Endocannabinoid Function.
Gray JM, Wilson CD, Lee TT, Pittman QJ, Deussing J, Hillard CJ, McEwen BS, Schulkin J, Karatsoreos IN, Patel S, Hill MN (2016)
Psychoneuroendocrinology 66, 151-158.
LINK
Divergent Responses of Inflammatory Mediators in the Amygdala and Prefrontal Cortex to Acute Psychological Stress.
Vecchiarelli HA, Gandhi CP, Gray JM, Morena M, Hassan KI, Hill MN (2016)
Brain, Behavior and Immunity 51, 70-91
LINK
2015
Corticotropin Releasing Hormone Drives Anandamide Hydrolysis in the Amygdala to Promote Anxiety.
Gray JM, Vecchiarelli HA, Morena M, Lee TT, Hermanson D, Kim AB, McLaughlin RJ, Hassan K, Kuhne C, Wotjak CT, Deussing JM, Patel S, Hill MN (2015).
Journal of Neuroscience 35(9), 3879-3892
LINK
A Peripheral Endocannabinoid Mechanism Contributes to Glucocorticoid-mediated Metabolic Syndrome.
Bowles NP, Karatsoreos IN, Li X, Vemuri VK, Wood JA, Li Z, Tamashiro K, Schwartz GJ, Makriyannis AM, Kunos G, Hillard CJ, McEwen BS, Hill MN (2015).
Proceedings of the National Academy of Sciences USA 112, 285-290
LINK
2013
Age of Stress Exposure Modulates Both the Immediate and Sustained Effects of Repeated Stress on Corticolimbic Cannabinoid CB1 Receptor Binding in Male Rats.
Lee TT, Hill MN (2013)
Neuroscience 249, 106-114.
LINK
COLLABORATIONS
2022
Anandamide and 2-arachidonoylglycerol differentially modulate autistic-like traits in a genetic model of autism based on FMR1 deletion in rats
Schiavi S#, Manduca A#, Carbone E, Buzzelli V, Rava A, Feo A, Ascone F, Morena M, Campolongo P, Hill MN, Trezza V (2022)
Neuropsychopharmacology (online ahead of print)
LINK
Cannabidiol Impairs Brain Mitochondrial Metabolism and Neuronal Integrity
Drummond-Main CD, Ahn Y, Kesler M, Gavrilovici C, Kim DY, Kiroski I, Baglot SL, Chen A, Sharkey KA, Hill MN, Teskey GC, Rho JM (2022)
Cannabis and Cannabinoid Research (online ahead of print)
LINK
Fatty acid amide hydrolase inhibition and N-arachidonoylethanolamine modulation by isoflavonoids: A novel target for upcoming antidepressants
Zada W, VanRyzin JW, Perez-Pouchoulen M, Baglot SL, Hill MN, Abbas G, Clark SM, Rashid U, McCarthy MM, Mannan A (2022)
Pharmacol Res Perspect 10(5):e00999
LINK
Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play
VanRyzin JW, Marquardt AE, Argue KJ, Vecchiarelli HA, Ashton SE, Arambula SE, Hill MN, McCarthy MM (2022)
Neuron 110(7):1271
LINK
2021
A Systematic Review and Meta-Analysis on the Effects of Exercise on the Endocannabinoid System
Desai S, Borg B, Cuttler C, Crombie KM, Rabinak CA, Hill MN, Marusak HA (2021)
Cannabis and Cannabinoid Research 7(4):388-408
LINK
Amygdalar endocannabinoids are affected by predator odor stress in a sex-specific manner and modulate acoustic startle reactivity in female rats
Albrechet-Souza L, Nastase AS, Hill MN, Gilpin NW (2021)
Neurobiology of Stress 15:100387
LINK
In vivo endocannabinoid dynamics at the timescale of physiological and pathological neural activity.
Farrell JS, Colangeli R, Dong A, George AG, Addo-Osafo K, Kingsley PJ, Morena M, Wolff MD, Dudok B, He K, Patrick TA, Sharkey KA, Patel S, Marnett LJ, Hill MN, Li Y, Teskey GC, Soltesz I (2021)
Neuron 109(15): 2398-2403
LINK
Interactive effects of compounding multidimensional stressors on maternal and male and female rat offspring outcomes.
Strzelewicz AR, Vecchiarelli HA, Rondón-Ortiz AN, Raneri A, Hill MN, Kentner AC (2021)
Hormones & Behavior 134, 105013
LINK
Cannabidiol Interferes with Establishment of Δ 9-Tetrahydrocannabinol-Induced Nausea Through a 5-HT 1A Mechanism
DeVuono MV, La Caprara O, Petrie GN, Limebeer CL, Rock EM, Hill MN, Parker LA (2021)
Cannabis and Cannabinoid Research, 7(1):58-64
LINK
Positive allosteric modulation of type 1 cannabinoid receptors reduces spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg
Roebuck AJ, Greba Q, Smolyakova AM, Alaverdashvili M, Marks WN, Garai S, Baglot SL, Petrie G, Cain SM, Snutch TP, Thakur GA, Hill MN, Howland JG, Laprairie RB. (2021)
Neuropharmacology, doi: 10.1016/j.neuropharm.2021.108553
LINK
Fatty acid amide hydrolase binding is inversely correlated with amygdalar functional connectivity: a combined positron emission tomography and magnetic resonance imaging study in healthy individuals
Green DGJ, Kim J, Kish SJ, Tyndale RF, Hill MN, Strafella AP, Tong J, McCluskey T, Westwood DJ, Houle S, Lobaugh NJ, Boileau I (2021)
Journal of Psychiatry & Neuroscience 46(2): 238-246.
LINK
Nausea-Induced Conditioned Gaping Reactions in Rats Produced by High-Dose Synthetic Cannabinoid, JWH-018.
DeVuono MV, Hrelja KM, Petrie GN, Limebeer CL, Rock EM, Hill MN, Parker LA (2021).
Cannabis and Cannabinoid Research 5(4): 298-304
LINK
Cannabis vapor self-administration elicits sex- and dose-specific alterations in stress reactivity in rats
Glodosky NC, Cuttler C, Freels TG, Wright HR, Rojas MJ, Baglot SL, Hill MN, McLaughlin RJ (2021).
Neurobiology of Stress 13:100260
LINK
2020
Hippocampal 2-Arachidonoyl Glycerol Signaling Regulates Time-of-Day- and Stress-Dependent Effects on Rat Short-Term Memory
Santori A, Morena M, Hill MN, Campolongo P (2020)
International Journal of Molecular Sciences 21(19):7316
LINK
The endocannabinoid system in humans: significant associations between anandamide, brain function during reward feedback and a personality measure of reward dependence
Redlich C, Dlugos A, Hill MN, Patel S, Korn D, Enneking V, Foerster K, Arolt V, Domschke K, Dannlowski U, Redlich R (2020)
Neuropsychopharmacology 46(5):1020-1027
LINK
Colonization with the commensal fungus Candida albicans perturbs the gut-brain axis through dysregulation of endocannabinoid signaling
Markey L, Hooper A, Melon LC, Baglot S, Hill MN, Maguire J, Kumamoto CA (2020)
Psychoneuroendocrinology 121:104808
LINK
Anandamide Signaling Augmentation Rescues Amygdala Synaptic Function and Comorbid Emotional Alterations in a Model of Epilepsy
Colangeli C, Morena M, Pittman QJ, Hill MN, Teskey GC (2020)
Journal of Neuroscience 40(31):6068-6081
LINK
Role of the stress response and the endocannabinoid system in Δ 9-tetrahydrocannabinol (THC)-induced nausea
DeVuono MV, Caprara OL, Sullivan MT, Bath A, Petrie GN, Limebeer CL, Rock EM, Hill MN, Parker LA (2020)
Psychopharmacology (Berlin) 237(7):2187-2199
LINK
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice.
Mock ED, Mustafa M, Gunduz-Cinar O, Cinar R, Petrie GN, Kantae V, Di X, Ogasawara D, Varga Z, Paloczi J, Miliano C, Donvito G, van Esbroeck ACM, van der Gracht AMF, Kotsogianni L, Park JK, Martella A, van der Wel T, Soethoudt M, Jiang M, Wendel TJ, Janssen APA, Bakker AT, Donovan CM, Castillo LI, Florea BI, Wat J, van den Hurk H, Wittwer M, Grether U, Holmes A, van Boeckel CAA, Hankemeier T, Cravatt BF, Buczynski MW, Hill MN, Pacher P, Lichtman AH, van der Stelt M (2020)
Nature Chemical Biology 16(6):667-675
LINK
Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice
Burgdorf CE, Jing D, Yang R, Huang C, Hill MN, Mackie K, Milner TA, Pickel VM, Lee FS, Rajadhyasha AM (2020)
Science Advances 6(7):eaay1502
LINK
Inhibition of Monoacylglycerol Lipase Activity Alters Prefrontal Cortical Excitability and Blunts the Effects of Traumatic Stress in Rat
Worley NB, Varela JA, Gaillardetz GP, Hill MN, Christianson JP (2020)
Neuropharmacology, 166:107964
LINK
Role of the Kynurenine Pathway and the Endocannabinoid System as Modulators of Inflammation and Personality Traits
Coccaro E, Heilman P, Hill MN, Coussons-Read M, Brundin L (2020)
Psychoneuroendocrinology, 110:104434
LINK
Protective Effects of Elevated Anandamide on Stress and Fear-related Behaviors: Translational Evidence from Humans and Mice
Mayo LM, Asratian A, Linde J, Holm L, Natt D, Augier G, Stensson N, Vecchiarelli HA, Balsevich G, Aukema RJ, Ghafouri B, Spagnolo PA, Lee FS, Hill MN, Heilig M (2020)
Molecular Psychiatry 25(5):993-1005
LINK
Endogenous Cannabinoid Levels and Suicidality in Combat Veterans
Sher L, Bierer L, Flory J, Hill MN, Makotkine I, Yehuda R (2020)
Psychiatry Research 287, 112495
LINK
Ghrelin Receptor Signaling is not Required for Glucocorticoid-induced Obesity in Male Mice
Hay RE, Edwards A, Klein M, Hyland L, McDonald D, Karatsoreos IN, Hill MN, Abizaid A (2020)
Endocrinology 161(3), bqz023
LINK
D3 Dopamine Receptors and a Missense Mutation of Fatty Acid Amide Hydrolase Linked in Mouse and Men: Implication for Addiction
Mansouri E, Nobrega JJ, Hill MN, Tyndale RF, Lee FS, Hendershot CS, Best LM, DiCiano P, Balsevich G, Kish SJ, Tong J, Le Foll B, Boileau I (2020)
Neuropsychopharmacology 45(5), 745-752
LINK
Endocannabinoid Genetic Variation Enhances Vulnerability to THC Reward in Adolescent Female Mice
Burgdorf CE, Jing D, Yang R, Huang C, Hill MN, Mackie K, Milner T, Pickel VM, Lee FS, Rajadhyaksa AM (2020)
Science Advances 6(7), eaay1502
LINK
Elevated Anandamide, Enhanced Fear Extinction and Attenuated Stress Responses Following Inhibition of Fatty Acid Amide Hydrolase (FAAH): A Randomized, Controlled Experimental Medicine Trial
Mayo LM, Asratian A, Linde J, Morena M, Haataja R, Hammer V, Augier G, Hill MN, Heilig M (2020)
Biological Psychiatry 87(6), 538-547
LINK
Vaporization of Cannabis Extracts has Reinforcing Properties and Supports Conditioned Drug-seeking Behavior in Rats
Freels TG, Baxter-Potter LN, Lugo JM, Wright HR, Glodosky NC, Baglot S, Petrie GN, Yu Z, Clowers BH, Cuttler C, Fuchs RA, Hill MN, McLaughlin RJ (2020).
Journal of Neuroscience 40(9), 1897-1908
LINK
Suppression of Presynaptic Glutamate Release by Postsynaptic Metabotropic NMDA Receptor Signaling to Pannexin-1
Bialecki J, Werner A, Weilinger NG, Tucker CM, Vecchiarelli HA, Egana J, Medizabal-Zubiaga J, Grandes P, Hill MN, Thompson RJ (2020)
Journal of Neuroscience 40(4), 729-742
LINK
2019
Anandamide Modulation of Circadian- and Stress-Dependent Effects on Rat Short-Term Memory
Santori A, Colucci P, Mancini GF, Morena M, Palmery M, Trezza V, Hill MN, Campolongo P (2019)
Psychoneuroendocrinology 108, 155-162
LINK
A FAAH-related Pseudogene Regulates Anandamide Levels and Pain Sensitivity. British Journal of Anesthesia
Habib AM, Okorokov AL, Hill MN, Bras, JT, Lee, MC, Gossage SJ, van Drimmelen M, Morena M, Houlden H, Ramirez JD, Bennett DL, Wood JN, Srivastava D, Cox JJ (2019)
British Journal of Anaesthesia 123(2), e249-e253
LINK
Microglial Phagocytosis of Newborn Cells is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play
Van Ryzin JW, Marquardt AE, Argue KJ, Vecchiarelli HA, Ashton SE, Arambula SE, Hill MN, McCarthy MM (2019)
Neuron 102(2), 435-449
LINK
2018
Prenatal Immune Activation Potentiates Endocannabinoid-related Plasticity of Inhibitory Synapses in the Hippocampus of Adolescent Rat Offspring
Guo Z, Tse YC, Zhang Y, Sun Q, Aukema R, Vecchiarelli HA, Hill MN, Wong TP, Boksa P (2018)
European Neuropsychopharmacology 28(12), 1408-1417
LINK
The Lateral Habenula Directs Coping Styles Under Conditions of Stress via Recruitment of the Endocannabinoid System
Berger AL, Henricks AM, Wright HR, Warrick CR, Lugo JM, Morena M, Sticht MA, Bonilla I, Craft RM, Parsons LH, Grandes P, Hillard CJ, Hill MN, McLaughlin RJ (2018)
Biological Psychiatry 84(8), 611-623
LINK
Plasma Endocannabinoids and Affect Regulation in Humans
Coccaro EF, Hill MN, Robinson L, Lee RJ (2018)
Psychoneuroendocrinology 92, 66-71
LINK
Enhancing Endocannabinoid Neurotransmission Augments the Efficacy of Extinction Training and Ameliorates Traumatic Stress-induced Behavioral Alterations in Rats
Morena M, Berardi A, Colucci P, Palmery M, Trezza V, Hill MN, Campolongo P (2018)
Neuropsychopharmacology 43(6), 1284-1296
LINK
Glucocorticoid-Endocannabinoid Uncoupling Mediates Fear Suppression Deficits After Early Life Stress
Atsak P, Morena M, Schoenmaker C, Tabak E, Oomen C, Jamil S, Hill MN, Roozendaal B (2018)
Psychoneuroendocrinology 91, 41-49
LINK
2017
Sex- and Hormone-dependent Alterations in Alcohol Withdrawal-induced Anxiety and Corticolimbic Endocannabinoid Signaling
Henricks AM, Berger AL, Lugo JM, Baxter-Potter LN, Bieniasz KV, Petrie G, Sticht MA, Hill MN, McLaughlin RJ (2017)
Neuropharmacology 124, 121-133
LINK
Early-life Inflammation with LPS Delays Fear Extinction in Adult Rodents
Doeni VM, Song CM, Hill MN, Pittman QJ (2017)
Brain Behavior and Immunity 63, 176-185
LINK
Significance of BDNF Val66Met Polymorphism in Brain Plasticity in Children
Myers KA, Vecchiarelli HA, Damji O, Keess J, Hill MN, Kirton A (2017)
Pediatric Neurology 66, e1-e2
LINK
MAGL Inhibitors Produce Rapid Antidepressant Responses via GABAergic Synaptic Depression
Wang Y, Gu N, Duan T, Kesner P, Blaskovits F, Liu J, Lu Y, Gao F, Harris C, Mackie K, Li J, Tang Q, Hill MN, Yuan Z, Zhang X (2017)
Molecular Psychiatry 22(2), 215-226
LINK
Δ9- Tetrahydrocannabinol Decreases Willingness to Exert Cognitive Effort in Male Rats
Silveira MM, Adams WK, Morena M, Hill MN, Winstanley CA (2017)
Journal of Psychiatry and Neuroscience 42(2), 131-138
LINK
2016
Deficient Adolescent Social Behavior Following Early Life Inflammation is Ameliorated by Augmenting Anandmide Signaling
Doeni V, Gray JM, Patel S, Hill MN, Pittman QJ (2016)
Brain, Behavior and Immunity 58, 237-247
LINK
p21 Activated Kinase-1 Restricts Tonic Endocannabinoid Signaling in the Hippocampus
Xia S, Zhou Z, Leung C, Morena M, Hill MN, Xie W, Jia Z (2016)
eLife 5, e14653
LINK
Effects of Maternal Stress and Perinatal Fluoxetine Exposure on Behavioral Outcomes in Adult Offspring
Kiryanova V, Iablokova SJ, Vecchiarelli HA, Hill MN, Dyck RH (2016)
Neuroscience 320, 281-296
LINK
Delta-9 Tetrahydrocannabinol (THC) Affects Forelimb Motor Map Expression but has Little Effect on Skilled and Unskilled Behavior
Scullion K, Guy AR, Singleton A, Spanswick S, Hill MN, Teskey GC (2016)
Neuroscience 319, 134-145
LINK
Inhibition of Anandamide Hydrolysis Dampens the Neuroendocrine Response to Stress in Neonatal Rats Subjected to Suboptimal Rearing Conditions
McLaughlin RJ, Verlezza S, Gray JM, Hill MN, Walker CD (2016)
Stress 19(1), 114-124
LINK
2015
Endocannabinoid Signaling in the Stress Response of Male and Female Songbirds
Dickens M, Vecchiarelli HA, Hill MN, Bentley G (2015)
Endocrinology 156(12), 4649-4659
LINK
Training Associated-Emotional Arousal Shapes Endocannabinoid Modulation of Spatial Memory Retrieval in Rats
Morena M, De Castro V, Gray JM, Palmery M, Trezza V, Roozendaal B, Hill MN, Campolongo P (2015)
Journal of Neuroscience 35(41), 13962-13974
LINK
A Robust Capillary LC-MS/MS Method for Quantitation of Neuromodulatory Endocannabinoids
Qi M, Morena M, Vecchiarelli HA, Hill MN, Schreimer DC (2015)
Rapid Communications in Mass Spectrometry 29(20), 1889-1897
LINK
Disruption of Peri-adolescent Endocannabinoid Signaling Modulates Neuroendocrine and Behavioral Responses to Stress in Adulthood
Lee TT, Hill MN, Hillard CJ, Gorzalka BB (2015)
Neuropharmacology 99, 89-97
LINK
Distinct Roles of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol in Social Behavior and Emotionality at Different Developmental Ages in Rats
Manduca A, Morena M, Campolongo P, Servadio M, Palmery M, Trabace L, Hill MN, Vanderschuren LM, Cuomo V, Trezza V (2015)
European Neuropsychopharmacology 25(8), 1362-74
LINK
Chronic Stress Induces Anxiety via an Amygdalar Intracellular Cascade that Impairs Endocannabinoid Signaling
Qin T, Zhou X, Pandey NR, Vecchiarelli HA, Stewart CA, Zhang X, Lagace DC, Brunel J, Beique JC, Stewart AF, Hill MN, Chen HH (2015)
Neuron 85(6), 1319-1331
LINK
FAAH Genetic Variation Enhances Frontoamygdala Function in Mouse and Human
Dincheva I, Drysdale AT, Hartley CA, Johnson DC, Jing DQ, King EC, Ra S, Gray JM, Yang RR, DeGruccio AM, Huang C, Cravatt BF, Glatt CE, Hill MN, Casey BJ, Lee FS (2015)
Nature Communications 6, 6395
LINK
Brain Derived Neurotrophic Factor and Subcallosal Deep Brain Stimulation Treatment for Refractory Depression
Ramasubbu R, Vecchiarelli HA, Hill MN, Kiss ZH (2015)
World Journal of Biological Psychiatry 16(2), 135-138
LINK
2013
Altered Cognitive-emotional Behavior in Early Experimental Autoimmune Encephalitis - Cytokine and Hormonal Correlates
Acharjee S, Nauyani N, Tsutsui M, Hill MN, Ousman S, Pittman QJ (2013)
Brain, Behavior and Immunity 33, 164-172
LINK
REVIEWS, EDITORIALS, AND COMMENTARIES
2021
Targeting the Endocannabinoid System in the Treatment of Posttraumatic Stress Disorder: A Promising Case of Preclinical-Clinical Translation?
Mayo LM, Rabinak CA, Hill MN, Heilig M (2021)
Biological Psychiatry S0006-3223(21)01472-4
LINK
Endocannabinoids, cannabinoids and the regulation of anxiety
Petrie GN, Nastase AS, Aukema RJ, Hill MN (2021)
Neuropharmacology 195:108626
LINK
2020
2-Arachidonoylglycerol Modulation of Anxiety and Stress Adaptation: From the Grass Roots to Novel Therapeutics
Bedse G, Hill MN, Patel S (2020)
Biological Psychiatry 88(7):520-530
LINK
In Memory of Bruce McEwen: A Gentle Giant of Neuroscience
Hill MN, Karatsoreos IN, de Kloet ER, Lupien S, Woolley CS (2020)
Nature Neuroscience 23(4), 473-474
LINK
2019
Buzzkill: The Consequences of Depleting Anandamide in the Hippocampus
Morena M, Hill MN (2019)
Neuropsychopharmacology 44(8), 1347-1348
LINK
2018
Prefrontal Endocannabinoids, Stress Controllability and Resilience: A Hypothesis
Worley NB, Hill MN, Christianson JP (2018)
Progress in Neuropsychopharmacology and Biological Psychiatry 85, 180-188
LINK
Towards Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Post-Traumatic Stress Disorder
Hill MN, Campolongo P, Yehuda R, Patel S (2018)
Neuropsychopharmacology 43(1), 80-102
LINK
Cannabis and Cannabinoids: From Synapse to Society
Haney M, Hill MN (2018)
Neuropsychopharmacology 43(1), 1-3
LINK
2017
Endocannabinoids: Effectors of Glucocorticoid Signaling
Balsevich G, Petrie GN, Hill MN (2017)
Frontiers in Neuroendocrinology 47, 86-108
LINK
Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential
Bogdan R, Salmeron BJ, Carey CE, Agrawal A, Calhoun VD, Garavan H, Hariri AR, Heinz A, Hill MN, Holmes A, Kalin NH, Goldman D (2017)
Biological Psychiatry 82(3), 165-175
LINK
The Endocannabinoid System as a Target for Novel Anxiolytic Drugs
Patel S, Hill MN, Cheer JF, Wotjak CT, Holmes A (2017)
Neuroscience and Biobehavioral Reviews 76, 56-66
LINK
2016
Endocannabinoids and Stress Resilience: Is Deficiency Sufficient to Promote Vulnerability?
Hill MN, Lee FS (2016)
Biological Psychiatry 79(10), 792-793
LINK
Developmental Regulation of Fear Learning and Anxiety Behavior by Endocannabinoids
Lee TT, Hill MN, Lee FS (2016)
Genes, Brain and Behavior 15(1), 108-124
LINK
Neurobiological Interactions Between Stress and the Endocannabinoid System
Morena M, Patel S, Bains JS, Hill MN (2016)
Neuropsychopharmacology 41(1), 80-102
LINK
2015
Mechanisms of Stress in the Brain
McEwen BS, Bowles NP, Gray J, Hill MN, Hunter RG, Karatsoreos IN, Nasca C (2015)
Nature Neuroscience 18(10), 1353-1363
LINK
Perspective: Be Clear About the Real Risks
Hill MN (2015)
Nature 525, S14
LINK
To Stress or Not to Stress: A Question of Models. Current Protocols in Neuroscience
Gray JM, Chaouloff F, Hill MN (2015)
Current Protocols in Neuroscience70, 8.33.1-8.33.22
LINK
2014
Clearing the Smoke: What do we know about the Relationship Between Adolescent Cannabis Use and Schizophrenia
Hill MN (2014)
Journal of Psychiatry and Neuroscience 39(2), 75-77
LINK
2013
Anandamide and FAAH in the Amygdala: Mediating Protection and Recovery from Stress
Gunduz-Cinar O, Hill MN, McEwen BS, Holmes A (2013)
Trends in Pharmacological Sciences 34(11), 637-644
LINK
Food for Thought: Hormonal, Experiental and Neural Correlates of Obesity
Karatsoreos IN, Thaler JP, Borgland SL, Champagne FA, Hurd Y, Hill MN (2013)
Journal of Neuroscience 33(45), 17610-17616
LINK
Translational Evidence for a Role of the Endocannabinoid System in Stress-related Psychiatric Illnesses
Hill MN, Patel S (2013)
Biology of Mood and Anxiety Disorders 3, 19
LINK
Targeting the Endocannabinoid System in the Treatment of Posttraumatic Stress Disorder: A Promising Case of Preclinical-Clinical Translation?
Mayo LM, Rabinak CA, Hill MN, Heilig M (2021)
Biological Psychiatry S0006-3223(21)01472-4
LINK
Endocannabinoids, cannabinoids and the regulation of anxiety
Petrie GN, Nastase AS, Aukema RJ, Hill MN (2021)
Neuropharmacology 195:108626
LINK
2020
2-Arachidonoylglycerol Modulation of Anxiety and Stress Adaptation: From the Grass Roots to Novel Therapeutics
Bedse G, Hill MN, Patel S (2020)
Biological Psychiatry 88(7):520-530
LINK
In Memory of Bruce McEwen: A Gentle Giant of Neuroscience
Hill MN, Karatsoreos IN, de Kloet ER, Lupien S, Woolley CS (2020)
Nature Neuroscience 23(4), 473-474
LINK
2019
Buzzkill: The Consequences of Depleting Anandamide in the Hippocampus
Morena M, Hill MN (2019)
Neuropsychopharmacology 44(8), 1347-1348
LINK
2018
Prefrontal Endocannabinoids, Stress Controllability and Resilience: A Hypothesis
Worley NB, Hill MN, Christianson JP (2018)
Progress in Neuropsychopharmacology and Biological Psychiatry 85, 180-188
LINK
Towards Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Post-Traumatic Stress Disorder
Hill MN, Campolongo P, Yehuda R, Patel S (2018)
Neuropsychopharmacology 43(1), 80-102
LINK
Cannabis and Cannabinoids: From Synapse to Society
Haney M, Hill MN (2018)
Neuropsychopharmacology 43(1), 1-3
LINK
2017
Endocannabinoids: Effectors of Glucocorticoid Signaling
Balsevich G, Petrie GN, Hill MN (2017)
Frontiers in Neuroendocrinology 47, 86-108
LINK
Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential
Bogdan R, Salmeron BJ, Carey CE, Agrawal A, Calhoun VD, Garavan H, Hariri AR, Heinz A, Hill MN, Holmes A, Kalin NH, Goldman D (2017)
Biological Psychiatry 82(3), 165-175
LINK
The Endocannabinoid System as a Target for Novel Anxiolytic Drugs
Patel S, Hill MN, Cheer JF, Wotjak CT, Holmes A (2017)
Neuroscience and Biobehavioral Reviews 76, 56-66
LINK
2016
Endocannabinoids and Stress Resilience: Is Deficiency Sufficient to Promote Vulnerability?
Hill MN, Lee FS (2016)
Biological Psychiatry 79(10), 792-793
LINK
Developmental Regulation of Fear Learning and Anxiety Behavior by Endocannabinoids
Lee TT, Hill MN, Lee FS (2016)
Genes, Brain and Behavior 15(1), 108-124
LINK
Neurobiological Interactions Between Stress and the Endocannabinoid System
Morena M, Patel S, Bains JS, Hill MN (2016)
Neuropsychopharmacology 41(1), 80-102
LINK
2015
Mechanisms of Stress in the Brain
McEwen BS, Bowles NP, Gray J, Hill MN, Hunter RG, Karatsoreos IN, Nasca C (2015)
Nature Neuroscience 18(10), 1353-1363
LINK
Perspective: Be Clear About the Real Risks
Hill MN (2015)
Nature 525, S14
LINK
To Stress or Not to Stress: A Question of Models. Current Protocols in Neuroscience
Gray JM, Chaouloff F, Hill MN (2015)
Current Protocols in Neuroscience70, 8.33.1-8.33.22
LINK
2014
Clearing the Smoke: What do we know about the Relationship Between Adolescent Cannabis Use and Schizophrenia
Hill MN (2014)
Journal of Psychiatry and Neuroscience 39(2), 75-77
LINK
2013
Anandamide and FAAH in the Amygdala: Mediating Protection and Recovery from Stress
Gunduz-Cinar O, Hill MN, McEwen BS, Holmes A (2013)
Trends in Pharmacological Sciences 34(11), 637-644
LINK
Food for Thought: Hormonal, Experiental and Neural Correlates of Obesity
Karatsoreos IN, Thaler JP, Borgland SL, Champagne FA, Hurd Y, Hill MN (2013)
Journal of Neuroscience 33(45), 17610-17616
LINK
Translational Evidence for a Role of the Endocannabinoid System in Stress-related Psychiatric Illnesses
Hill MN, Patel S (2013)
Biology of Mood and Anxiety Disorders 3, 19
LINK
